Desmoids are a unique subset of soft tissue tumors.  While they can cause symptoms related to local progression, they do not metastasize and a subset have indolent behavior, in some cases regressing spontaneously.  Because surgery for desmoids can be morbid and recurrence rates are high, non-operative treatment has become the preferred treatment strategy for desmoid patients.  Active observation, regional therapies for anatomically appropriate cases and medical therapies can all be employed in patients with desmoid-type fibromatosis.  Cases requiring non-operative management will be discussed to assist listeners in integrating recently published data into their practices.